Vitamin-D Deficiency: A Neglected Topic Alarms the Health Care Providers
Keywords:
Vitamin-D, Osteoporosis, Arthritis, RicketsAbstract
ABSTRACT
Objective: To assess the vitamin D3 in the study population and to compare it in the male female gender.
Methods: This observational study was conducted from November 2016 to April 2017. Total 200 patients were selected through inclusion and exclusion criteria. Student’s t-test and SPSS version 20 to compare the mean levels of vitamin D3 in male and female gender
Results: Male female ratio was found to be 1:1. Vitamin –D deficiency was found to be more prevalent in male gender as compared to females. Mean of the serum vitamin –D levels were 15.10+9.2ng/dl in men while it was 17.4+13.4 ng/dl in women. 139(69.5%) of the study population was found deficiency <20ng/ml while 31(15.5%) were having insufficient levels<30ng/ml and only 30(15%) showed normal levels 30-50ng/ml. There was a significant difference between the two genders with p value 0.000
Conclusion: Vitamin –D deficiency is very common in both genders of all age groups and males are more deficient as compared to female.
References
2. Afshan Kamran, Syed Mahboob Alam, Farida Qadir. Prevalence of vitamin D deficiency and insufficiency among adult asthamatic patients of Karachi. Pak .J. Pharm, 2014 Nov; 27(6):2139-2144.
3. Syed Zaryab Ahmed, Anila Jaleel, Kamran Hameed, Farah Ahmed, Hasan Danish, Azhar Chugtai. et al. Serum vitamin D concentration in Asthamatic children and its association with recovery time from an asthma exacerbation. BJMMR, 2015 Aug;10(6):1-10.
4. Sumayya Aftab. Frequency of nutrition rickets in children and association with iron deficiency anemia. JFJMC 2013 Sep;7(3):38-39.
5. Deepandra Garg, Vikas K. Sharma, B. S. Karnawat Association of serum vitamin D with acute lower respiratory infection in Indian children under 5 years: a case control study. Int J Contemp Pediatr.2016 Aug;3(4):1164-1169.
6. A. Khakshour. A.S. Farhat. A. Mohammad Zadeh. The association between 25-dehydroxy vitamin D and lower respiratory infections in children aged lessthan 5 years in Imam Reza hospital, Bojnurd, Iran. J Pak Med Assoc. 2013; 65(11):1153-1155.
7. Nighat H. Abdul Ghaffare N. Khalid Mehmood A. Khan. Frequency nutritional rickets in children admitted with severe pneumonia. J Pak Med Assoc. 2010 Sep; 60(9):729-732.
8. Kazi MY. Aamir K. Rana MN. Farooq MA. Frequency of vitamin D deficiency in children presenting with frequent sino-pulmonary infections. Pak Pediatr J. 2013; 37(2):101-105.
9. Lee JA, Hwang JS, Hwang IT, Kim DH, Seo JH, Lim JS. Low vitamin D levels are associated with iron deficiency anemia in children and adolescents. Pediatr Hematol Oncol.2015; 32(2):99-108.
10. Memon S. Shaikh F. Makhdoom A. Tahir SM. Serum 25-Hydroxy Vitamin D; Parathormone and bone mineral density: co-relation in children. Professional Med J 2017 Mar; 24(3):375-380.
11. Edmondo F, David B, Carlo F, Giovanda F, Annarosa C, Cmet S et al. Vitamin D binding protein Gene polymorphism and base line vitamin D levels as predictors of Antiviral response in chronic hepatitis C. Hepatology 2012 Nov;56(5)1641-1650.
12. Rahimoon, Abdul Ghani, Maheshwari Sunil Dat, Memon Ndeem, Rajput Muhsin Shafee. Chronic liver disease; vitamin D deficiency in the patients. Professional Med J 2015; 22(7):844-848.
13. Ahmad G. Hashmat N. Satti NK. Hypovitaminosis D; In children in ambulatory setting in Riyadh. Professional Med J 2015;22(12):1535-1540.
14. Daniel D. Bikle. Agents that affect bone mineral homeostasis. In Katzung text book of Pharmacology 12th edition Mc Graw Hill, USA.2012;769-787.
















